Only one top-25 game is on Wednesday’s college basketball schedule. That matchup is the UConn Huskies taking on the DePaul Blue Demons at Wintrust Arena. Looking for ATS picks? See below.

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AP Top 25 Picks ATS Today

DePaul Blue Demons vs. No. 11 UConn Huskies

Spread Prediction

• Computer Prediction: UConn 76, DePaul 74
• Projected Favorite: UConn by 2.1 points
• Pick ATS: DePaul (+10.5)

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Key Facts

• Time: 2:00 PM ET
• Location: Chicago, Illinois
• Venue: Wintrust Arena
• TV Channel: CBS Sports Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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